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Baypamun® action in hamsters experimentally infected with Leptospira interrogans serogroup Canicola Braz. J. Vet. Res. Anim. Sci.
LANGONI,Hélio; SEABRA JÚNIOR,Rui; CABRAL,Kenio Gouveia; CUNHA,Eva Laurice Pereira.
Baypamun® is an immunity modulator recommended as prophylactic and therapeutic use. In the present study, this product was used in the hamsters experimentally infected with Leptospira interrogans serogroup canicola. The animals were divided in 5 groups, with 20 animals each. This product was used as a therapeutic, prophylactic and as adjuvant. As a therapeutic use all the animals died. Despite of eight (40.0%) survivors, the prophylactic use wasn't also totally favorable due to leptospire recovering from kidneys of those animals. Based on the analysis of antibodies levels among animals that received vaccine and vaccine with Baypamun® as adjuvante, this product didn't conferred superior humoral answer. However, other studies should be accomplished utilizing...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Immunomodulators; Leptospira; Immunity.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-95962001000600010
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